About the Trial

If you are currently motivated to quit smoking, you may be interested in a clinical research study we are conducting for smoking cessation.

We are looking for men and women:

• Between the ages of 18 and 75
• Currently smoking ten or more cigarettes per day
• Motivated to quit smoking

We are specifically looking for people both with and without a history of a mental health disorder.

Those eligible to join the study will need to attend 15 outpatient visits over a 24-week period. You will also need to be available for 11 phone calls during the study. You will follow a course of active treatment for 12 weeks and receive varenicline, bupropion, transdermal nicotine patch or placebo (an inactive substance that looks like the study drugs). You will not know whether you receive one of the study drugs or placebo and neither will the study doctor. After you complete the 12 weeks of active treatment, there is an additional 12 week non-treatment follow-up phase.

You are expected to abstain from using any tobacco products and taking any form of nicotine replacement therapy during the entire study. All participants will receive brief counseling and support for smoking cessation at each clinic visit.

Please provide your contact information to receive a call with more information about the smoking cessation program. Or, you can find a participating facility nearest to you by visiting the Find A Location page.